Wdr33 | WD repeat domain 33

GeneMGI:1921570Synonyms: WDC146, 1110001N06Rik, +3 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsWdr33em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased prepulse inhibition3 supporting datasetsWdr33em1(IMPC)TcpheterozygoteEarly adult4.64x10-8 
embryonic lethality prior to organogenesis1 supporting datasetWdr33em1(IMPC)TcphomozygoteE9.5N/A * 
decreased mean corpuscular hemoglobin concentration1 supporting datasetWdr33em1(IMPC)TcpheterozygoteEarly adult5.18x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wdr33em1(IMPC)TcpIndelmouse
Wdr33tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Wdr33tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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