Mtmr3 | myotubularin related protein 3

GeneMGI:1921552Synonyms: ZFYVE10, 1700092A20Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological

14 No significant impact

6 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

increased circulating alkaline phosphatase level1 supporting datasetMtmr3tm1b(EUCOMM)HmguhomozygoteEarly adult1.9x10-10 
impaired pupillary reflex1 supporting datasetMtmr3tm1b(EUCOMM)HmguhomozygoteEarly adult1.45x10-6 
increased circulating potassium level1 supporting datasetMtmr3tm1b(EUCOMM)HmguhomozygoteEarly adult7.26x10-5 
decreased mean corpuscular volume1 supporting datasetMtmr3tm1b(EUCOMM)HmguhomozygoteEarly adult8.87x10-8 
increased startle reflex1 supporting datasetMtmr3tm1b(EUCOMM)HmguhomozygoteEarly adult6.79x10-7 
impaired glucose tolerance1 supporting datasetMtmr3tm1b(EUCOMM)HmguhomozygoteEarly adult1.93x10-9 
decreased mean corpuscular hemoglobin1 supporting datasetMtmr3tm1b(EUCOMM)HmguhomozygoteEarly adult0 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mtmr3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Mtmr3tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Mtmr3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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