Septin14 | septin 14

GeneMGI:1921472Synonyms: 1700016K13Rik, Sept14

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Hematopoietic system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular hemoglobin concentration1 supporting datasetSeptin14em1(IMPC)TcphomozygoteEarly adult3.97x10-6 
decreased mean corpuscular volume1 supporting datasetSeptin14em1(IMPC)TcphomozygoteEarly adult2.36x10-6 
abnormal lens morphology1 supporting datasetSeptin14em1(IMPC)TcphomozygoteEarly adult7.4x10-5 
decreased hematocrit1 supporting datasetSeptin14em1(IMPC)TcphomozygoteEarly adult2.54x10-5 
increased circulating alanine transaminase level1 supporting datasetSeptin14em1(IMPC)TcphomozygoteEarly adult7.12x10-37 
cataract1 supporting datasetSeptin14em1(IMPC)TcphomozygoteEarly adult8.35x10-5 
increased circulating aspartate transaminase level1 supporting datasetSeptin14em1(IMPC)TcphomozygoteEarly adult7.99x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Septin14em1(IMPC)TcpExon Deletionmouse
Septin14tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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