Acbd5 | acyl-Coenzyme A binding domain containing 5

GeneMGI:1921409Synonyms: 1300014E15Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased bone mineral content	2 supporting datasets	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.12x10^-6
increased lean body mass	2 supporting datasets	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.03x10^-6
increased mean platelet volume	1 supporting dataset	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.08x10^-8
increased circulating alkaline phosphatase level	1 supporting dataset	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.24x10^-6
decreased circulating total protein level	1 supporting dataset	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.8x10^-6
decreased bone trabecula number	1 supporting dataset	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.5x10^-7
improved glucose tolerance	1 supporting dataset	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.98x10^-6
decreased circulating triglyceride level	1 supporting dataset	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.26x10^-5
increased bone mineral density	1 supporting dataset	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.97x10^-5
abnormal gait	1 supporting dataset	Acbd5^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.09x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Acbd5.

Associated images

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Histopathology

There is no histopathology data found for Acbd5.

IMPC related publications

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External links

No external links available for Acbd5.

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*Acbd5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Acbd5^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Acbd5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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