Krt80 | keratin 80

GeneMGI:1921377Synonyms: 1200016G03Rik, Kb20, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cornea opacity1 supporting datasetKrt80em1(IMPC)JhomozygoteLate adult5.44x10-7 
abnormal lens morphology1 supporting datasetKrt80em1(IMPC)JhomozygoteLate adult4.12x10-8 
hyperactivity7 supporting datasetsKrt80em1(IMPC)JhomozygoteLate adult1.83x10-22 
increased vertical activity1 supporting datasetKrt80em1(IMPC)JhomozygoteLate adult3.52x10-9 
decreased circulating glucose level1 supporting datasetKrt80em1(IMPC)JhomozygoteLate adult2.21x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Krt80em1(IMPC)JExon Deletionmouse
Krt80tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Krt80tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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