Pi16 | peptidase inhibitor 16

GeneMGI:1921366Synonyms: 1200009H11Rik

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Vision/eye Skeleton Renal/urinary system

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal testis morphology1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adult6.64x10-5 
persistence of hyaloid vascular system1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adult3.55x10-7 
increased bone mineral density1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adult1.52x10-5 
increased circulating bilirubin level1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adult2.51x10-5 
abnormal kidney morphology1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged testis1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetPi16em1(IMPC)MbphomozygoteEarly adult9.94x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pi16em1(IMPC)MbpExon Deletionmouse
Pi16tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Pi16tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Pi16tm2a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Pi16tm2e(KOMP)MbpTargeted, non-conditional alleleES Cell

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