Tmco1 | transmembrane and coiled-coil domains 1

GeneMGI:1921173Synonyms: ESTM39, 1190006A08Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Reproductive system Immune system Vision/eye Hematopoietic system Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



female infertility	1 supporting dataset	Tmco1^em1(IMPC)J	homozygote	Early adult	N/A ^*
cornea opacity	1 supporting dataset	Tmco1^em1(IMPC)J	heterozygote	Early adult	3.05x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Tmco1^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased leukocyte cell number	1 supporting dataset	Tmco1^em1(IMPC)J	heterozygote	Early adult	2.7x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmco1.

Associated images

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Histopathology

There is no histopathology data found for Tmco1.

IMPC related publications

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External links

No external links available for Tmco1.

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*Tmco1^em1(IMPC)J*	Exon Deletion	‌	mouse

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