Fam161a | family with sequence similarity 161, member A

GeneMGI:1921123Synonyms: 4930430E16Rik

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Nervous system Vision/eye Behavior/neurological Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

2Associated diseases

Expression examined in:52Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



increased grip strength	3 supporting datasets	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.22x10^-6
decreased coping response	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.83x10^-5
increased lean body mass	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.88x10^-5
decreased circulating cholesterol level	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.4x10^-7
increased circulating sodium level	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.47x10^-5
decreased exploration in new environment	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.91x10^-5
abnormal optic disk morphology	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.37x10^-7
abnormal lens morphology	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.85x10^-9
abnormal retina blood vessel morphology	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.7x10^-11
abnormal retina morphology	1 supporting dataset	Fam161a^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.05x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fam161a.

Associated images

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Histopathology

There is no histopathology data found for Fam161a.

IMPC related publications

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External links

No external links available for Fam161a.

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*Fam161a^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Fam161a^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fam161a^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fam161a^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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