Neurl4 | neuralized E3 ubiquitin protein ligase 4

GeneMGI:1921092Synonyms: 0610025P10Rik

Physiological systems

20 / 24 physiological systems tested

13 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Adipose tissue Growth/size/body region Nervous system Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

7 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:19Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal eye morphology	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
increased lean body mass	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Early adult	1.27x10^-6
abnormal kidney morphology	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
decreased heart weight	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Late adult	2.55x10^-5
enlarged gallbladder	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
small kidney	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
increased grip strength	1 supporting dataset	Neurl4^em1(IMPC)Mbp	homozygote	Middle aged adult	4.89x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Neurl4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Neurl4.

IMPC related publications

Loading...

External links

No external links available for Neurl4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Neurl4^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Neurl4^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Neurl4^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

My Genes