Thap1 | THAP domain containing, apoptosis associated protein 1

GeneMGI:1921004Synonyms: 4833431A01Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Embryo Growth/size/body region Vision/eye Behavior/neurological Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased grip strength	1 supporting dataset	Thap1^em1(IMPC)J	heterozygote	Early adult	7.65x10^-5
embryonic growth retardation	1 supporting dataset	Thap1^em1(IMPC)J	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Thap1^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal cornea morphology	1 supporting dataset	Thap1^em1(IMPC)J	heterozygote	Early adult	1.63x10^-5
embryonic lethality prior to tooth bud stage	1 supporting dataset	Thap1^em1(IMPC)J	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Thap1.

Associated images

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Histopathology

There is no histopathology data found for Thap1.

IMPC related publications

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External links

No external links available for Thap1.

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*Thap1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Thap1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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