Lima1 | LIM domain and actin binding 1

GeneMGI:1920992Synonyms: EPLIN, epithelial protein lost in neoplasm, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsLima1tm1b(KOMP)WtsihomozygoteEarly adult6.32x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetLima1tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lima1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lima1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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