Mcmbp | minichromosome maintenance complex binding protein

GeneMGI:1920977Synonyms: 1110007A13Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Hematopoietic system Skeleton Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Mcmbp^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	Mcmbp^em1(IMPC)J	heterozygote	Early adult	4.64x10^-6
decreased mean corpuscular volume	1 supporting dataset	Mcmbp^em1(IMPC)J	heterozygote	Early adult	3.66x10^-6
decreased bone mineral density	1 supporting dataset	Mcmbp^em1(IMPC)J	heterozygote	Early adult	4.47x10^-6
embryonic lethality prior to organogenesis	1 supporting dataset	Mcmbp^em1(IMPC)J	homozygote	E9.5	N/A ^*
decreased lean body mass	1 supporting dataset	Mcmbp^em1(IMPC)J	heterozygote	Early adult	7.42x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mcmbp.

Associated images

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Histopathology

There is no histopathology data found for Mcmbp.

IMPC related publications

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External links

No external links available for Mcmbp.

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*Mcmbp^em1(IMPC)J*	Exon Deletion	‌	mouse

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