Fbrsl1 | fibrosin-like 1

GeneMGI:1920907Synonyms: Gm29766, 2410025L10Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

8 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased grip strength	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	9.56x10^-5
small thymus	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
vertebral fusion	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	6.72x10^-5
abnormal liver morphology	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
small epididymis	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
small seminal vesicle	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	9.21x10^-7
abnormal sternum morphology	1 supporting dataset	Fbrsl1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbrsl1.

Associated images

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Histopathology

There is no histopathology data found for Fbrsl1.

IMPC related publications

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External links

No external links available for Fbrsl1.

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*Fbrsl1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Fbrsl1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fbrsl1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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