Ddx46 | DEAD box helicase 46

GeneMGI:1920895Synonyms: 8430438J23Rik, 2200005K02Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetDdx46em1(IMPC)TcphomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsDdx46em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased mean corpuscular hemoglobin1 supporting datasetDdx46em1(IMPC)TcpheterozygoteEarly adult1.02x10-5 
enlarged lymph nodes1 supporting datasetDdx46em1(IMPC)TcpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ddx46em1(IMPC)TcpExon Deletionmouse

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