Marveld3 | MARVEL (membrane-associating) domain containing 3

GeneMGI:1920858Synonyms: Mrvldc3, MARVD3, +1 more

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Skeleton Cardiovascular system Renal/urinary system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal digit morphology	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.99x10^-8
abnormal spleen morphology	2 supporting datasets	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal vertebral arch morphology	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.99x10^-6
abnormal rib morphology	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.79x10^-5
enlarged heart	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.48x10^-6
increased kidney weight	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.02x10^-5
rib fusion	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.94x10^-5
abnormal thymus morphology	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Marveld3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Marveld3.

Associated images

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Histopathology

There is no histopathology data found for Marveld3.

IMPC related publications

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External links

No external links available for Marveld3.

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*Marveld3^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Marveld3^{tm45743(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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