Dcbld2 | discoidin, CUB and LCCL domain containing 2

GeneMGI:1920629Synonyms: CLCP1, Esdn, +1 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased anti-nuclear antigen antibody level	2 supporting datasets	Dcbld2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal vertebral arch morphology	1 supporting dataset	Dcbld2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.87x10^-5
trunk curl	1 supporting dataset	Dcbld2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.04x10^-5
increased heart weight	1 supporting dataset	Dcbld2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.65x10^-10
decreased circulating fructosamine level	1 supporting dataset	Dcbld2^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.41x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dcbld2.

Associated images

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Histopathology

There is no histopathology data found for Dcbld2.

IMPC related publications

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External links

No external links available for Dcbld2.

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*Dcbld2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Dcbld2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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