Sppl2b | signal peptide peptidase like 2B

GeneMGI:1920468Synonyms: 3110056O03Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Cardiovascular system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina blood vessel morphology	1 supporting dataset	Sppl2b^em1(IMPC)Tcp	homozygote	Early adult	7.27x10^-5
abnormal retina vasculature morphology	1 supporting dataset	Sppl2b^em1(IMPC)Tcp	homozygote	Early adult	7.29x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sppl2b.

Associated images

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Histopathology

There is no histopathology data found for Sppl2b.

IMPC related publications

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External links

No external links available for Sppl2b.

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*Sppl2b^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Sppl2b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Sppl2b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Sppl2b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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