Nwd2 | NACHT and WD repeat domain containing 2

GeneMGI:1920464Synonyms: B830017A01Rik, 3110047P20Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	8 supporting datasets	Nwd2^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.95x10^-14
enlarged seminal vesicle	1 supporting dataset	Nwd2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Nwd2^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased body weight	2 supporting datasets	Nwd2^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.93x10^-6
decreased anxiety-related response	1 supporting dataset	Nwd2^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.74x10^-14
decreased CD8-positive, naive alpha-beta T cell number	1 supporting dataset	Nwd2^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.57x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Nwd2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Nwd2.

IMPC related publications

Loading...

External links

No external links available for Nwd2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Nwd2^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Nwd2^{tm97149(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes