Wdr37 | WD repeat domain 37

GeneMGI:1920393Synonyms: 4933417A01Rik, 3110035P10Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Skeleton

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	2 supporting datasets	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	8.79x10^-6
fusion of vertebral arches	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.67x10^-7
increased circulating insulin level	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	8.95x10^-8
increased bone mineral content	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.41x10^-5
kyphosis	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.53x10^-6
vertebral fusion	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.92x10^-5
increased circulating calcium level	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.8x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.59x10^-5
decreased leukocyte cell number	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.56x10^-6
abnormal spine curvature	1 supporting dataset	Wdr37^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.04x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Wdr37.

Associated images

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Histopathology

There is no histopathology data found for Wdr37.

IMPC related publications

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External links

No external links available for Wdr37.

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*Wdr37^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

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