Sgip1 | SH3-domain GRB2-like (endophilin) interacting protein 1

GeneMGI:1920344Synonyms: 3110007P09Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Limbs/digits/tail Vision/eye Behavior/neurological Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



hyperactivity	2 supporting datasets	Sgip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.43x10^-6
increased startle reflex	1 supporting dataset	Sgip1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.83x10^-5
abnormal digit morphology	1 supporting dataset	Sgip1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.37x10^-6
increased circulating lipase level	1 supporting dataset	Sgip1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.62x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Sgip1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.74x10^-5
abnormal nail morphology	1 supporting dataset	Sgip1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.49x10^-6
abnormal lens morphology	2 supporting datasets	Sgip1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.5x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sgip1.

Associated images

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Histopathology

There is no histopathology data found for Sgip1.

IMPC related publications

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External links

No external links available for Sgip1.

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*Sgip1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Sgip1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Sgip1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Sgip1^{tm39126(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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