Tmem138 | transmembrane protein 138

GeneMGI:1920232Synonyms: 1700113I01Rik, 2900055D14Rik

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

10 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetTmem138tm1b(EUCOMM)WtsihomozygoteEarly adult9.08x10-5 
decreased bone mineral content2 supporting datasetsTmem138tm1b(EUCOMM)WtsihomozygoteEarly adult4.84x10-7 
increased spleen weight1 supporting datasetTmem138tm1b(EUCOMM)WtsihomozygoteEarly adult1.5x10-5 
thick ventricular wall1 supporting datasetTmem138tm1b(EUCOMM)WtsihomozygoteEarly adult3.65x10-6 
decreased body length1 supporting datasetTmem138tm1b(EUCOMM)WtsihomozygoteEarly adult1.87x10-5 
decreased prepulse inhibition1 supporting datasetTmem138tm1b(EUCOMM)WtsihomozygoteEarly adult7.17x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmem138tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Tmem138tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tmem138tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Tmem138tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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