Dip2c | disco interacting protein 2 homolog C

GeneMGI:1920179Synonyms: 2900024P20Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Mortality/aging Renal/urinary system

13 No significant impact

3 Not tested

Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged urinary bladder1 supporting datasetDip2cem1(IMPC)TcpheterozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance2 supporting datasetsDip2cem1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged adrenal glands1 supporting datasetDip2cem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal sternum morphology1 supporting datasetDip2cem1(IMPC)TcphomozygoteEarly adultN/A * 
increased monocyte cell number1 supporting datasetDip2cem1(IMPC)TcpheterozygoteEarly adult4.13x10-6 
abnormal uterus morphology1 supporting datasetDip2cem1(IMPC)TcpheterozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetDip2cem1(IMPC)TcpheterozygoteEarly adultN/A * 
small thymus1 supporting datasetDip2cem1(IMPC)TcpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dip2cem1(IMPC)TcpExon Deletionmouse
Dip2ctm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dip2ctm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Dip2ctm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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