Pfn4 | profilin family, member 4
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Limbs/digits/tail Respiratory system
18 No significant impact
3 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| increased pulmonary respiratory rate | 1 supporting dataset | Pfn4tm1b(KOMP)Wtsi | homozygote | Early adult | 5.31x10-5 | ||
| decreased pulmonary ventilation | 2 supporting datasets | Pfn4tm1b(KOMP)Wtsi | homozygote | Early adult | 2.22x10-7 | ||
| abnormal tail morphology | 1 supporting dataset | Pfn4tm1b(KOMP)Wtsi | homozygote | Early adult | 5.2x10-6 | ||
| decreased bronchoconstrictive response | 1 supporting dataset | Pfn4tm1b(KOMP)Wtsi | homozygote | Early adult | 4.03x10-5 |
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External links
No external links available for Pfn4.
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| Pfn4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Pfn4tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pfn4tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Pfn4tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pfn4tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |