Cox15 | cytochrome c oxidase assembly protein 15
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Mortality/aging Cardiovascular system
18 No significant impact
2 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Cox15tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| increased heart atrium size | 1 supporting dataset | Cox15tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Cox15tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.44x10-9 | ||
| abnormal heart morphology | 1 supporting dataset | Cox15tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Cox15tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Cox15tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Cox15tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.64x10-9 | ||
| increased heart weight | 1 supporting dataset | Cox15tm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.72x10-5 |
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External links
No external links available for Cox15.
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| Cox15tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Cox15tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Cox15tm44809(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |