Prdm4 | PR domain containing 4

GeneMGI:1920093Synonyms: 2810470D21Rik, SC1, +2 more

Physiological systems

20 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Muscle Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Renal/urinary system

8 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



impaired glucose tolerance	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.16x10^-6
abnormal heart left ventricle morphology	4 supporting datasets	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.92x10^-10
microphthalmia	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
short tibia	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.66x10^-5
abnormal cornea morphology	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.81x10^-6
absent spleen	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased lean body mass	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.98x10^-7
thick ventricular wall	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.49x10^-6
abnormal gait	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.08x10^-7
abnormal iris morphology	1 supporting dataset	Prdm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.48x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Prdm4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Prdm4.

IMPC related publications

Loading...

External links

No external links available for Prdm4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Prdm4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Prdm4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Prdm4^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Prdm4^{tm1c(EUCOMM)Hmgu}*	Wild type floxed exon (post-Flp)	‌	mouse
*Prdm4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes