Dhx30 | DExH-box helicase 30
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues
| increased circulating free fatty acids level | 1 supporting dataset | Dhx30tm1.1(KOMP)Vlcg | heterozygote | Early adult | 7.18x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Dhx30tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| increased startle reflex | 1 supporting dataset | Dhx30tm1.1(KOMP)Vlcg | heterozygote | Early adult | 9.52x10-5 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Dhx30tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.05x10-12 | ||
| decreased circulating glucose level | 1 supporting dataset | Dhx30tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.84x10-11 | ||
| decreased locomotor activity | 1 supporting dataset | Dhx30tm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.02x10-5 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Dhx30tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| increased circulating sodium level | 1 supporting dataset | Dhx30tm1.1(KOMP)Vlcg | heterozygote | Early adult | 7.9x10-5 |
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External links
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| Dhx30tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Dhx30tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Dhx30tm78724(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |