Sass6 | SAS-6 centriolar assembly protein
Physiological systems
17 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Cardiovascular system Mortality/aging Craniofacial
8 No significant impact
7 Not tested
Data collections
Gene metrics:20Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal embryo turning | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| edema | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal neural tube closure | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal optic vesicle formation | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Sass6em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal heart looping | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| pale yolk sac | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal hindbrain development | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
| abnormal neural tube morphology | 1 supporting dataset | Sass6em1(IMPC)Bay | homozygote | E9.5 | N/A * |
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External links
No external links available for Sass6.
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| Sass6em1(IMPC)Bay | Exon Deletion | | mouse |
| Sass6tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sass6tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |