Tmem161b | transmembrane protein 161B

GeneMGI:1919995Synonyms: 2810446P07Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Skeleton Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased lean body mass	1 supporting dataset	Tmem161b^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	5x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Tmem161b^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased total body fat amount	2 supporting datasets	Tmem161b^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	3.81x10^-8
decreased bone mineral content	1 supporting dataset	Tmem161b^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	7.81x10^-5
decreased circulating serum albumin level	1 supporting dataset	Tmem161b^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	3.44x10^-5
decreased circulating total protein level	1 supporting dataset	Tmem161b^{tm2b(EUCOMM)Hmgu}	heterozygote	Early adult	1.67x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem161b.

Associated images

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Histopathology

There is no histopathology data found for Tmem161b.

IMPC related publications

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External links

No external links available for Tmem161b.

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*Tmem161b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Tmem161b^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tmem161b^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tmem161b^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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