Ints8 | integrator complex subunit 8

GeneMGI:1919906Synonyms: D130008D20Rik, 2810013E07Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased mean corpuscular hemoglobin concentration	1 supporting dataset	Ints8^em1(IMPC)Tcp	heterozygote	Early adult	4.86x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Ints8^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	2 supporting datasets	Ints8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Ints8^em1(IMPC)Tcp	heterozygote	Early adult	4.11x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ints8.

Associated images

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Histopathology

There is no histopathology data found for Ints8.

IMPC related publications

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External links

No external links available for Ints8.

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*Ints8^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Ints8^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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