Pan3 | PAN3 poly(A) specific ribonuclease subunit

GeneMGI:1919837Synonyms: 2700050F09Rik, A430027N15Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Integument Digestive/alimentary Hematopoietic system Skeleton Mortality/aging

13 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes1 supporting datasetPan3em1(IMPC)TcpheterozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsPan3em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetPan3em1(IMPC)TcpheterozygoteEarly adultN/A * 
abnormal sternum morphology1 supporting datasetPan3em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal sternum morphology1 supporting datasetPan3em1(IMPC)TcpheterozygoteEarly adultN/A * 
decreased mean corpuscular hemoglobin1 supporting datasetPan3em1(IMPC)TcpheterozygoteEarly adult2.29x10-7 
enlarged cecum1 supporting datasetPan3em1(IMPC)TcpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pan3em1(IMPC)TcpExon Deletionmouse

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