Tagap1 | T cell activation GTPase activating protein 1

GeneMGI:1919786Synonyms: 2610315E15Rik

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



microphthalmia	1 supporting dataset	Tagap1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Tagap1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
increased blood urea nitrogen level	1 supporting dataset	Tagap1^em1(IMPC)Tcp	homozygote	Early adult	1.67x10^-5
enlarged kidney	1 supporting dataset	Tagap1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
decreased circulating triglyceride level	1 supporting dataset	Tagap1^em1(IMPC)Tcp	homozygote	Early adult	1.35x10^-5
enlarged lymph nodes	1 supporting dataset	Tagap1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Tagap1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
decreased circulating cholesterol level	1 supporting dataset	Tagap1^em1(IMPC)Tcp	homozygote	Early adult	2.56x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Tagap1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Tagap1.

IMPC related publications

Loading...

External links

No external links available for Tagap1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Tagap1^em1(IMPC)Tcp*	Inter-exon deletion	‌	mouse
*Tagap1^{tm107802(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Tagap1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes