Ier5l | immediate early response 5-like

GeneMGI:1919750Synonyms: 2610524G09Rik

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Vision/eye Behavior/neurological Skeleton Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased heart weight1 supporting datasetIer5lem1(IMPC)JhomozygoteEarly adult1.46x10-5 
decreased locomotor activity5 supporting datasetsIer5lem1(IMPC)JhomozygoteEarly adult1.73x10-5 
abnormal bone structure1 supporting datasetIer5lem1(IMPC)JhomozygoteEarly adult2.99x10-7 
hyperactivity1 supporting datasetIer5lem1(IMPC)JhomozygoteEarly adult4.08x10-5 
abnormal retina blood vessel morphology1 supporting datasetIer5lem1(IMPC)JhomozygoteEarly adult6.44x10-10 
decreased bone mineral content2 supporting datasetsIer5lem1(IMPC)JhomozygoteEarly adult1.04x10-8 
increased circulating phosphate level1 supporting datasetIer5lem1(IMPC)JhomozygoteEarly adult6.87x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ier5lem1(IMPC)JExon Deletionmouse

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