Sgo1 | shugoshin 1
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
| abnormal lens morphology | 1 supporting dataset | Sgo1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.06x10-5 | ||
| increased circulating bilirubin level | 1 supporting dataset | Sgo1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.55x10-5 | ||
| decreased circulating cholesterol level | 1 supporting dataset | Sgo1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.24x10-5 | ||
| decreased circulating HDL cholesterol level | 1 supporting dataset | Sgo1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.3x10-6 | ||
| increased circulating creatinine level | 1 supporting dataset | Sgo1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 9.29x10-12 | ||
| cataract | 1 supporting dataset | Sgo1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.57x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Sgo1tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Sgo1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Sgo1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Sgo1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |
| Sgo1tm47338(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |