Brap | BRCA1 associated protein
Physiological systems
22 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Embryo Growth/size/body region Nervous system Behavior/neurological Cardiovascular system Mortality/aging
14 No significant impact
2 Not tested
Data collections
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| edema | 1 supporting dataset | Brapem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Brapem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| hemorrhage | 1 supporting dataset | Brapem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| abnormal blood vessel morphology | 1 supporting dataset | Brapem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Brapem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| abnormal neural tube morphology | 1 supporting dataset | Brapem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Brapem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Brapem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| increased freezing behavior | 1 supporting dataset | Brapem1(IMPC)Mbp | heterozygote | Early adult | 3.51x10-18 | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Brapem1(IMPC)Mbp | homozygote | E15.5 | N/A * |
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External links
No external links available for Brap.
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| Brapem1(IMPC)Mbp | Exon Deletion | | mouse |