Faim2 | Fas apoptotic inhibitory molecule 2

GeneMGI:1919643Synonyms: NMP25, Tmbim2, +3 more

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased kidney weight1 supporting datasetFaim2em1(IMPC)CcpczhomozygoteEarly adult2.04x10-8 
enlarged kidney1 supporting datasetFaim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
small spleen1 supporting datasetFaim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
cataract1 supporting datasetFaim2em1(IMPC)CcpczhomozygoteEarly adult6.58x10-5 
abnormal kidney morphology1 supporting datasetFaim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetFaim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Faim2em1(IMPC)CcpczExon Deletionmouse
Faim2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Faim2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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