Tmem175 | transmembrane protein 175

GeneMGI:1919642Synonyms: 3010001K23Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Pigmentation Integument Endocrine/exocrine gland

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal coat/hair pigmentation	2 supporting datasets	Tmem175^{tm1b(KOMP)Wtsi}	homozygote	Middle aged adult	4.93x10^-9
abnormal coat/hair pigmentation	2 supporting datasets	Tmem175^{tm1b(KOMP)Wtsi}	homozygote	Late adult	1.08x10^-6
increased circulating aspartate transaminase level	1 supporting dataset	Tmem175^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.08x10^-5
abnormal seminal vesicle morphology	1 supporting dataset	Tmem175^{tm1b(KOMP)Wtsi}	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem175.

Associated images

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Histopathology

There is no histopathology data found for Tmem175.

IMPC related publications

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External links

No external links available for Tmem175.

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*Tmem175^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tmem175^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tmem175^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Tmem175^{tm45108(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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