2210408I21Rik | RIKEN cDNA 2210408I21 gene

GeneMGI:1919621

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Nervous system Skeleton Renal/urinary system

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small superior vagus ganglion	1 supporting dataset	2210408I21Rik^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased total body fat amount	2 supporting datasets	2210408I21Rik^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.71x10^-9
decreased bone mineral density	1 supporting dataset	2210408I21Rik^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.1x10^-17
decreased lean body mass	1 supporting dataset	2210408I21Rik^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.33x10^-8
hydrometra	1 supporting dataset	2210408I21Rik^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	2210408I21Rik^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
impaired glucose tolerance	1 supporting dataset	2210408I21Rik^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.64x10^-5
decreased bone mineral content	2 supporting datasets	2210408I21Rik^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.82x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for 2210408I21Rik.

Associated images

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Histopathology

There is no histopathology data found for 2210408I21Rik.

IMPC related publications

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External links

No external links available for 2210408I21Rik.

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*2210408I21Rik^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*2210408I21Rik^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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