Fbxl20 | F-box and leucine-rich repeat protein 20

GeneMGI:1919444Synonyms: 4632423N09Rik, Fbl2, +4 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Fbxl20^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased mean corpuscular volume	1 supporting dataset	Fbxl20^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	9.3x10^-6
increased mean platelet volume	1 supporting dataset	Fbxl20^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.99x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbxl20.

Associated images

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Histopathology

There is no histopathology data found for Fbxl20.

IMPC related publications

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External links

No external links available for Fbxl20.

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*Fbxl20^{em2(IMPC)Marc}*	Deletion	‌	mouse
*Fbxl20^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fbxl20^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fbxl20^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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