Snx6 | sorting nexin 6

GeneMGI:1919433Synonyms: 2810425K19Rik, 2610032J07Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsSnx6em1(IMPC)JhomozygoteEarly adult7.78x10-5 
increased circulating cholesterol level1 supporting datasetSnx6em1(IMPC)JhomozygoteEarly adult8.11x10-11 
decreased locomotor activity1 supporting datasetSnx6em1(IMPC)JhomozygoteEarly adult6.29x10-5 
increased circulating HDL cholesterol level1 supporting datasetSnx6em1(IMPC)JhomozygoteEarly adult3.93x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Snx6em1(IMPC)JExon Deletionmouse
Snx6tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Snx6tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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