Aifm3 | apoptosis-inducing factor, mitochondrion-associated 3

GeneMGI:1919418Synonyms: 2810401C16Rik

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating aspartate transaminase level1 supporting datasetAifm3em1(IMPC)RbrchomozygoteEarly adult6.05x10-5 
abnormal circulating LDL cholesterol level1 supporting datasetAifm3em1(IMPC)RbrchomozygoteLate adult3.74x10-8 
abnormal cholesterol homeostasis1 supporting datasetAifm3em1(IMPC)RbrchomozygoteLate adult6.64x10-5 
increased fasting circulating glucose level1 supporting datasetAifm3em1(IMPC)RbrchomozygoteEarly adult3.95x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aifm3em1(IMPC)RbrcExon Deletionmouse
Aifm3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Aifm3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Aifm3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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