Tmem163 | transmembrane protein 163

GeneMGI:1919410Synonyms: 2610024A01Rik, SV31

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Adipose tissue Growth/size/body region Vision/eye Skeleton Cardiovascular system Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



eye hemorrhage	1 supporting dataset	Tmem163^em1(IMPC)Mbp	homozygote	Early adult	1.46x10^-5
abnormal kidney morphology	2 supporting datasets	Tmem163^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased circulating insulin level	1 supporting dataset	Tmem163^em1(IMPC)Mbp	homozygote	Early adult	3.18x10^-14
abnormal skin coloration	1 supporting dataset	Tmem163^{em1(IMPC)Kmpc}	homozygote	Early adult	6.28x10^-5
abnormal bone structure	1 supporting dataset	Tmem163^{em1(IMPC)Kmpc}	homozygote	Early adult	8.87x10^-6
decreased bone mineral density	1 supporting dataset	Tmem163^{em1(IMPC)Kmpc}	homozygote	Early adult	4.61x10^-12
increased total body fat amount	1 supporting dataset	Tmem163^{em1(IMPC)Kmpc}	homozygote	Early adult	8.38x10^-7
abnormal coat/hair pigmentation	1 supporting dataset	Tmem163^{em1(IMPC)Kmpc}	homozygote	Early adult	7.91x10^-5
small kidney	2 supporting datasets	Tmem163^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased lean body mass	1 supporting dataset	Tmem163^{em1(IMPC)Kmpc}	homozygote	Early adult	1.55x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem163.

Associated images

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Histopathology

There is no histopathology data found for Tmem163.

IMPC related publications

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External links

No external links available for Tmem163.

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*Tmem163^{em1(IMPC)Kmpc}*	Exon Deletion	‌	mouse
*Tmem163^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Tmem163^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tmem163^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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