Rfc5 | replication factor C (activator 1) 5

GeneMGI:1919401Synonyms: 2610020K06Rik, 36.5kDa, +3 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased circulating phosphate level	1 supporting dataset	Rfc5^em1(IMPC)J	heterozygote	Early adult	1.85x10^-7
decreased heart rate	1 supporting dataset	Rfc5^em1(IMPC)J	heterozygote	Early adult	4.37x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Rfc5^em1(IMPC)J	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Rfc5^em1(IMPC)J	homozygote	E9.5	N/A ^*
prolonged RR interval	1 supporting dataset	Rfc5^em1(IMPC)J	heterozygote	Early adult	1.36x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rfc5.

Associated images

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Histopathology

There is no histopathology data found for Rfc5.

IMPC related publications

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External links

No external links available for Rfc5.

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*Rfc5^em1(IMPC)J*	Exon Deletion	‌	mouse
*Rfc5^{tm373439(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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