Adpgk | ADP-dependent glucokinase

GeneMGI:1919391Synonyms: 2610017G09Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Behavior/neurological Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased lean body mass	1 supporting dataset	Adpgk^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	1.69x10^-5
decreased total body fat amount	1 supporting dataset	Adpgk^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	8.76x10^-6
increased bone mineral content	1 supporting dataset	Adpgk^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	4.82x10^-5
increased bone mineral density	1 supporting dataset	Adpgk^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	9.71x10^-5
increased grip strength	2 supporting datasets	Adpgk^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	7.11x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adpgk.

Associated images

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Histopathology

There is no histopathology data found for Adpgk.

IMPC related publications

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External links

No external links available for Adpgk.

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*Adpgk^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Adpgk^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Adpgk^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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