Trub1 | TruB pseudouridine (psi) synthase family member 1

GeneMGI:1919383Synonyms: 9030425C13Rik, 2610009I02Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

15 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

increased circulating aspartate transaminase level1 supporting datasetTrub1tm1b(EUCOMM)HmguhomozygoteEarly adult4.66x10-27 
decreased mean corpuscular volume1 supporting datasetTrub1tm1b(EUCOMM)HmguhomozygoteEarly adult9.9x10-5 
thrombocytosis1 supporting datasetTrub1tm1b(EUCOMM)HmguhomozygoteEarly adult3.06x10-5 
increased circulating creatine kinase level1 supporting datasetTrub1tm1b(EUCOMM)HmguhomozygoteEarly adult8.01x10-5 
decreased circulating creatinine level1 supporting datasetTrub1tm1b(EUCOMM)HmguhomozygoteEarly adult4.78x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trub1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Trub1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Trub1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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