Tmub2 | transmembrane and ubiquitin-like domain containing 2

GeneMGI:1919303Synonyms: 2010008E23Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lymphocyte cell number	1 supporting dataset	Tmub2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.68x10^-5
increased startle reflex	1 supporting dataset	Tmub2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.64x10^-5
increased eosinophil cell number	1 supporting dataset	Tmub2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.29x10^-5
increased bone mineral content	1 supporting dataset	Tmub2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.87x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmub2.

Associated images

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Histopathology

There is no histopathology data found for Tmub2.

IMPC related publications

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External links

No external links available for Tmub2.

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*Tmub2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tmub2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tmub2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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