Pard3b | par-3 family cell polarity regulator beta

GeneMGI:1919301Synonyms: PAR3beta, Als2cr19, +5 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Muscle Vision/eye Behavior/neurological Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased cardiac muscle contractility	1 supporting dataset	Pard3b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.03x10^-5
abnormal lens morphology	1 supporting dataset	Pard3b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.2x10^-5
hyperactivity	2 supporting datasets	Pard3b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.54x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Pard3b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.77x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pard3b.

Associated images

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Histopathology

There is no histopathology data found for Pard3b.

IMPC related publications

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External links

No external links available for Pard3b.

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*Pard3b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pard3b^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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