Mccc1 | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)

GeneMGI:1919289Synonyms: MCCalpha, 1810045E08Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Vision/eye Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Mccc1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal retina outer nuclear layer morphology	1 supporting dataset	Mccc1^em1(IMPC)Bay	heterozygote	Early adult	5.12x10^-5
abnormal embryo size	1 supporting dataset	Mccc1^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
decreased total retina thickness	1 supporting dataset	Mccc1^em1(IMPC)Bay	heterozygote	Early adult	5.65x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mccc1.

Associated images

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Histopathology

There is no histopathology data found for Mccc1.

IMPC related publications

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External links

No external links available for Mccc1.

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*Mccc1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Mccc1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mccc1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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