Tedc2 | tubulin epsilon and delta complex 2

GeneMGI:1919266Synonyms: 1600002H07Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Pigmentation Integument Embryo Behavior/neurological Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetTedc2em1(IMPC)JhomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetTedc2em1(IMPC)JhomozygoteE12.5N/A * 
abnormal coat/hair pigmentation1 supporting datasetTedc2em1(IMPC)JheterozygoteEarly adult2.71x10-9 
abnormal embryo turning1 supporting datasetTedc2em1(IMPC)JhomozygoteE9.5N/A * 
abnormal vocalization1 supporting datasetTedc2em1(IMPC)JheterozygoteEarly adult6.79x10-8 
decreased grip strength3 supporting datasetsTedc2em1(IMPC)JheterozygoteEarly adult2.55x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tedc2em1(IMPC)JExon Deletionmouse
Tedc2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tedc2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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