Fndc3b | fibronectin type III domain containing 3B

GeneMGI:1919257Synonyms: 1600019O04Rik, fad104

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Pigmentation Integument Growth/size/body region Vision/eye Cardiovascular system Mortality/aging Renal/urinary system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal coat/hair pigmentation	1 supporting dataset	Fndc3b^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.49x10^-9
abnormal epididymis morphology	1 supporting dataset	Fndc3b^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Fndc3b^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Fndc3b^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
urinary bladder obstruction	1 supporting dataset	Fndc3b^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Fndc3b^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Fndc3b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased heart weight	2 supporting datasets	Fndc3b^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.21x10^-6
enlarged heart	1 supporting dataset	Fndc3b^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fndc3b.

Associated images

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Histopathology

There is no histopathology data found for Fndc3b.

IMPC related publications

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External links

No external links available for Fndc3b.

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*Fndc3b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Fndc3b^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Fndc3b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fndc3b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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