Atad3a | ATPase family, AAA domain containing 3A

GeneMGI:1919214Synonyms: Tob3, 2400004H09Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

8Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased circulating HDL cholesterol level	1 supporting dataset	Atad3a^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	6.13x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Atad3a^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating cholesterol level	1 supporting dataset	Atad3a^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	5.11x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atad3a.

Associated images

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Histopathology

There is no histopathology data found for Atad3a.

IMPC related publications

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External links

No external links available for Atad3a.

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*Atad3a^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Atad3a^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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